Polymorphisms of Crystalline Solids :: Chemistry Engineering Science Essays

pleomorphisms of quartz glassline Solids Polymorphism is the phenomenon where a compound can precipitate to arrive at numerous watch crystal structures. Due to space and time limitations, we redeem decided to confine the screen background of this paper to only include polymorphisms of crystalline solids and not include polymorphisms associated with deoxyribonucleic acid and genetic related topics. It is important in numerous atomic quash 18as of technology, that people are aware of the presence of polymorphisms and the properties of the different polymorphisms. The different crystalline structures each have different physical properties, which can change the use of the chemical. The physical properties that whitethorn differ from one polymorphism to another include solubility, density, melting foreland and even color. One of the variables that affect the crystallization process is the result that is use in the precipitation. The solvent may cause less stab le polymorphisms to form instead of those that are more stable. Predictions can be made as to which polymorphism will be formed based on the solvent and its properties. The mixing conditions also have an affect on the formation of conglomerate polymorphisms. (Meyerson) Different polymorphisms can also be formed by manipulating the solute concentrations, flows rates, and equipment configurations. explore involving polymorphisms is becoming increasingly important to the pharmaceutical industry due to the number of pharmaceuticals that are prone to polymorphisms, patents on certain polymorphisms, the differing bioavailability of the polymorphisms and the differing effects of the polymorphisms on the body. (Meyerson) During the 1970s, G.M.J. Schmidt coined the destination crystal engineering and defined it as predicting the crystal structure of solid state organic molecules (Sharma). In 1989, G.R. Desiraju revised the meaning as the the understanding of intermolecular interactions in the context of crystal packing and in the legalization of such(prenominal) understanding and the design of new solids with desired physical and chemical properties (Sharma). Crystal engineering has grown to encompass the study of the hardness and color of solids, nanotechnology, protein sense organ binding, pharmaceutical development, and polymorphisms (Sharma). Crystals are used in many areas of science, pharmaceuticals, and materials engineering. Crystals differ from many other organic and inorganic materials because of their ability to form polymorphisms.